The structure data table includes a column called "Overall Probability." This column displays the probability that the corresponding structure is the correct one given all available forms of data.
Note: although BayesFold only returns the 100 likeliest structures for an alignment, the overall probability is calculated based on the entire set of structures tested. This means that the overall probability will not sum to one.
By examining the overall probabilities for the returned structures, one can determine whether they are in fact very likely or are only marginally likely. If the total of the overall probabilities is low, it suggests that the likeliest 100 structures are in fact not much more likely than the discarded structures.
The structure table also includes a "Current Probability" column. This displays the probability of the corresponding structure given the data for each evidence that has data displayed. For example, if you have displayed the Folding Energy Score and Mismatch Best Index columns, the Current Probability column will display the combination of the conditional probabilities for the Energy and Mismatch evidences.
This functionality allows you to easily examine the effects of each evidence on the probability of a given structure. It also offers a simple way to discount the contribution from any evidence that is considered unreliable.
These conditional probabilities are combined by repeated applications of Bayes' Theorem. Each conditional probability (probability of the finding an evidence's data if the corresponding structure is the true one) is transformed into the probability of that the structure is the true one, given the evidence's data. This probability is then used as input to redo same calculation--this time using the next displayed evidence's conditional probability. In this manner multiple conditional probabilities are combined into the current probability.
When no evidences have data displayed (as in the default view of the table), the Current Probability column displays the total probability for each structure, identical to the contents of the "Overall Probability" column.